Antipater (ca. 46 BC – 4 BC) was Herod the Great's first-born son, his only child by his first wife Doris. He was named after his paternal grandfather Antipater the Idumaean. He and his mother were exiled after Herod divorced her between 43 BC and 40 BC to marry Mariamne I. However, he was recalled following Mariamne's fall and in 13 BC Herod made him his first heir in his will. He retained this position even when Alexandros and Aristobulos (Herod's sons by Mariamne) rose in the royal succession a year later, and even became exclusive successor to the throne after their execution in 7 BC (with Herod Philip I in second place).

However, in 5 BC Antipater was brought before Publius Quinctilius Varus, then Roman governor of Syria, charged with the intended murder of his father Herod. Antipater was found guilty by Varus; however, due to Antipater's high rank, it was necessary for Caesar Augustus to approve of the recommended sentence of death. After the guilty verdict, Antipater's position as exclusive successor was removed and granted to Herod Antipas. Once the sentence had approval from Augustus in 4 BC, Antipater was then executed, and Archelaus (from the marriage with Malthace) was made heir in his father will as king over Herod's entire kingdom (with Antipas and Philip as Tetrarchs over certain territories).

We know two of Antipater's wives through the writings of Josephus. First was his niece Mariamne III, daughter of Aristobulus IV.^[1] The second was a high-ranking Hasmonean princes whose first name is lost to history. She was the daughter of Antigonus the Hasmonean, the last Hasmonean king who also served as high priest. This wife of Antipater was also a first cousin of Mariamne I, renowned royal wife of Herod the Great. Josephus records that she was at the palace with Doris, Antipater's mother, in support of her husband during his trial before Varus in 5 B.C.E.^[2]